Dr. Li-Lian Gan

Oncology | Medicine | Clinical Research | Medical and Scientific Writing

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 Cancers | Volume 12, Issue 7. •

Molecular Mechanisms and Potential Therapeutic Reversal of Pancreatic Cancer-Induced Immune Evasion

Pancreatic cancer is one of the deadliest malignancies known to mankind. The Global Cancer Statistics 2018 (GLOBOCAN) ranks pancreatic cancer as the seventh leading cause of cancer death in both males and females, with an estimated 459,000 cases and 430,000 deaths in 2018 globally [ 1 ]. With an estimated five-year survival rate of 10% or less [ 2 ], pancreatic cancer is the cancer with the highest incidence-to-mortality ratio among all solid tumors [ 3 ]. Pancreatic cancer has also surpassed br
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 Cancers | Volume 14, Issue 15. •

Histone Deacetylase Inhibitors Restore Cancer Cell Sensitivity towards T Lymphocytes Mediated Cytotoxicity in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy and is often called the silent killer due to its lack of early and disease-specific clinical symptoms until the disease is advanced. Global Cancer Statistics 2020 (GLOBOCAN) ranks PDAC as the seventh leading cause of cancer death in both males and females. With an estimated five-year survival rate of 10% or less, pancreatic cancer is predicted to become the second leading cause of cancer death in the USA by 2030...
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Medical Journal of Malaysia Case Reports (MJM Case Reports) | Issue 1, Volume 1 •

An unusual pathogen in a typical clinical scenario: Pseudomonas oryzihabitans urosepsis in a patient with Myelodysplastic syndrome

Pseudomonas oryzihabitans (formerly known as Flavimonas oryzihabitans) is a gram-negative rod-shaped aerobic bacillus, an uncommon pathogen which acts as an opportunistic pathogen in immunocompromised patients. It has been reported in both humans and as a zoonotic pathogen. In this case, we detected this relatively unusual pathogen in a patient with a background of myelodysplastic syndrome (MDS) and numerous other chronic co-morbidities.
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Medical Journal of Malaysia | Vol. 77 No.3 •

Adverse events following BNT162b2 mRNA COVID-19 vaccination among healthcare workers: A single-centre experience in Malaysia

The COVID-19 pandemic is a global health crisis that has resulted in a massive disease burden worldwide. Mass vaccination plays an important role in controlling the spread and severity of COVID-19 infections worldwide. The findings of this study reinforce the safety of the BNT162b2 mRNA vaccine in the local population. The main adverse events were mild, although they occurred in most patients.